BEGIN:VCALENDAR VERSION:2.0 PRODID:www.eu-parc.eu BEGIN:VEVENT UID:69f3b14a108c3 DTSTART:20251209T130000Z SEQUENCE:0 TRANSP:OPAQUE DTEND:20251209T140000Z SUMMARY: Data-driven Design of Fish Cell Line-based Reproductive Toxicity A ssays CLASS:PUBLIC DESCRIPTION:The NC3Rs hosted a webinar on Data‑Driven Design of Fish Cell Line‑Based Reproductive Toxicity Assays on 9 December 2025\, from 14:00 to 15:00 CET. This free\, one‑hour online session presented key outcome s from the SAFE CRACK IT Challenge\, a collaborative initiative led by aQu aTox Solutions GmbH\, Eawag\, and the National Institute of Biology (Slove nia)\, aimed at advancing New Approach Methodologies (NAMs) to reduce reli ance on in vivo fish testing for environmental risk assessment. Participan ts learned about a novel computational pipeline for identifying reproducti ve toxicity biomarkers\, expression data generated from rainbow trout live r and testis cell lines\, and machine‑learning models built on historica l and newly generated in vitro and in vivo datasets.Target audienceThis we binar was particularly suited for ecotoxicologists and regulatory scientis ts from industry\, academia\, and government agencies involved in the deve lopment\, evaluation\, or regulatory acceptance of NAMs. X-ALT-DESC;FMTTYPE=text/html:

The NC3Rs hosted a webinar on Data‑Driven Design of Fish Cell Line‑Based Reproduct ive Toxicity Assays on 9 December 2025\, from 14:00 to 15:00 CET. Thi s free\, one‑hour online session presented key outcomes from the SAFE CR ACK IT Challenge\, a collaborative initiative led by aQuaTox Solutions Gmb H\, Eawag\, and the National Institute of Biology (Slovenia)\, aimed at ad vancing New Approach Methodologies (NAMs) to reduce reliance on in vivo fi sh testing for environmental risk assessment. Participants learned about a novel computational pipeline for identifying reproductive toxicity biomar kers\, expression data generated from rainbow trout liver and testis cell lines\, and machine‑learning models built on historical and newly genera ted in vitro and in vivo datasets.

Target audience< br>This webinar was particularly suited for ecotoxicologists and regulator y scientists from industry\, academia\, and government agencies involved i n the development\, evaluation\, or regulatory acceptance of NAMs.

DTSTAMP:20260430T194514Z END:VEVENT END:VCALENDAR