PARC organised an in-person training course on Chemical Exposure & Modelling, which took place from 10 to 12 June 2024 at Masaryk University, RECETOX, in Brno, Czech Republic, under the scientific coordination of Petra Růžičková and Klára Komprdová. The course focused on key aspects of exposure assessment and modelling, including the identification of input data, description of modelling processes, and the use of physiologically based kinetic (PBK) models to reconstruct or estimate chemical human exposure levels.

Training content

• Identification of sources of exposure data relevant for exposure modelling 

• Understanding of spatial data and the ability to process and display such data

• Critical assessment of exposure factors and model input data

• Performance of basic exposure assessments for example compounds

• Description of the basic concepts and principles of PBPK models

• Use of models for the estimation of internal levels of chemicals

• Critical assessment of model uncertainties

Target audience
The course was designed for researchers and students with basic knowledge of data use. Selection was based on applicants’ background, experience, and motivation, with priority given to PARC members.

Practical details
The course was free of charge, but participants covered their own travel, accommodation, and other expenses.

Training highlights
For a detailed summary of the training outcomes and participation, please click here. Training materials developed and used during the training were not made publicly available, but you can find other related training resources in the PARC Repository of Learning and Educational Materials.