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A sound management of chemicals is essential to implement many, if not all, UN Sustainable Development Goals. The UN (Global Environmental Outlook) and the EU Green Deal, call for measures to secure a non-toxic environment. The total number of industrial chemicals in commerce globally was conservatively estimated at 40.000 to 60.000. More than 60% of the volume of chemicals in the EU are classified as hazardous to human health, while around 35% are hazardous to the environment. Our knowledge about exposure to and toxicology of chemicals is relatively limited. Moreover, the methods to obtain data and data storage are not well harmonised which complicates data exchange.