What does the future of chemical safety look like? For 38 researchers, regulators, and scientists from around the world, the answer became clearer earlier this month in Brno, Czech Republic. Gathered for an intensive three-day training on new approach methodologies (NAMs) and hazard assessment, they explored cutting-edge tools that are set to reshape how chemicals are tested, moving beyond traditional methods towards more innovative, efficient, and humane approaches.

The course on NAMs and hazard assessment of chemicals, an integral part of the first PARC training plan, was successfully conducted from 11 to 13 June 2025, under the scientific coordination of RECETOX, Masaryk University ↗. The event gathered participants from 23 countries (Austria, Belgium, Colombia, Czechia, Denmark, Egypt, France, Germany, Greece, Hungary, China, Iceland, Italy, the Netherlands, Norway, Poland, Portugal, Serbia, Slovenia, Spain, Sweden, the United Kingdom, and the United States).

Throughout the three-day programme, experts from six countries – Czech Republic, Germany, Sweden, France, Poland, and United Kingdom – turned the course in more than lectures and technical terms. It was hands-on, practical, and focused on real-world application. From identifying developmental neurotoxicants and endocrine disruptors to exploring in silico tools and lab-based assays, participants got to experience the science behind NAMs in action.

Participants got introduced to NAMs for identifying developmental neurotoxicants, non-genotoxic carcinogens (NGTxCs), or endocrine and metabolic disruptors, as well as Omics technologies and explored topics related to implementing NAMs in regulatory contexts. Participants also gained practical hands-on experience with in silico approaches and in vitro assays for measuring gap junction intercellular communication (GJIC) or Aryl hydrocarbon receptor (AhR) activity. 

The balance between theoretical knowledge and applied practice was particularly appreciated by participants. 

The course was really well put together – clear, engaging, and full of useful content. I especially appreciated the balance between theory and practical examples, which made it easier to visualize how things work. A fantastic experience, said Magdalena, one of the trainees, from Poland.

This course provided a comprehensive learning experience thanks to brilliant lecturers and lab teams. Thank you for offering different perspectives on NAMs and their role in regulation and hazard assessment from a European point of view. I look forward to sharing this with my colleagues in the United States, added Sarah, another participant from the United States.

The course was also a positive experience for the lecturers, who appreciated the organisation and atmosphere. 

The workshop was successful, with participants showing strong engagement and satisfaction. They actively completed assigned tasks and contributed to productive discussions. The tasks were well-prepared, and the flexible planning allowed for smooth handling of minor issues. Several participants, primarily data specialists, appreciated the hands-on lab experience, which enhanced their understanding of laboratory procedures and terminology, shared Eliska, a hands-on workshop lecturer from the Czech Republic.

Further training opportunities will be announced on the PARC website. Stay tunned.