Nonsteroidal anti-inflammatory drugs (NSAIDs), such as indomethacin, are widely used but are also a leading cause of gastric ulcers due to their effects on the stomach lining.

A recent experimental study in rats shows that carnosic acid, a natural compound found in rosemary, significantly reduced gastric injury caused by NSAIDs. The effect was comparable to a standard gastroprotective medicine and was linked to both antioxidant activity and reduced inflammation.

The study also highlights the role of cellular defence mechanisms, suggesting that carnosic acid may help the body better respond to oxidative stress and tissue damage.

These findings add to growing evidence on the potential of plant-derived compounds in mitigating drug-induced side effects. Further research is needed to confirm relevance for human health and possible applications.

Read full paper here.