This seminar discusses in vitro tools to assess toxicology of chemical mixtures.

Presents industry perspectives on QSAR and read-across for regulatory toxicology, focusing on genotoxicity assessment of pesticide residues and the integration of chemical similarity, metabolism, and structural alerts.

Introduces next-generation PBK modeling and its role in translating in vitro concentrations to human-relevant exposures for risk assessment, highlighting key parameters, tools, and case studies.

Explore the EU Commission's proposed framework for Safe and Sustainable by Design (SSbD). This workshop discusses its stepwise process, assessment methods, and key aspects of implementation. Case studies and next steps in the criteria’s development are also explored.

The session outlines how stakeholder comments have influenced revisions to the proposed framework. It also includes a presentation of the updated framework and key changes introduced.

The webinar focus on methods to evaluate combined exposures and chemical mixtures, using computer models and in vivo/in vitro testing.

Introduces the fundamentals of deep learning and its application in toxicology, with a focus on model construction, input data handling, and potential uses such as QSAR enhancement.