This seminar discusses in vitro tools to assess toxicology of chemical mixtures.

Presents industry perspectives on QSAR and read-across for regulatory toxicology, focusing on genotoxicity assessment of pesticide residues and the integration of chemical similarity, metabolism, and structural alerts.

Introduces next-generation PBK modeling and its role in translating in vitro concentrations to human-relevant exposures for risk assessment, highlighting key parameters, tools, and case studies.

Covers key features and future plans for the QSAR Toolbox, including integration with IUCLID and applications in non-animal hazard assessment.

Explore the EU Commission's proposed framework for Safe and Sustainable by Design (SSbD). This workshop discusses its stepwise process, assessment methods, and key aspects of implementation. Case studies and next steps in the criteria’s development are also explored.

The session outlines how stakeholder comments have influenced revisions to the proposed framework. It also includes a presentation of the updated framework and key changes introduced.

Explores the concept, misconceptions, and future potential of AOPs in predictive toxicology, featuring case studies from nanosafety and discussing their integration with data-driven and high-throughput strategies.

Introduces the fundamentals of deep learning and its application in toxicology, with a focus on model construction, input data handling, and potential uses such as QSAR enhancement.

This handbook provides a comprehensive guide to nanosafety, with sections on data management, nanoinformatics, and emerging topics. Included is a detailed subsection on Safe-and-Sustainable-by-Design (SSbD), addressing the framework for safety and sustainability in material innovation.

Webinar on stakeholder use of the OECD QSAR Toolbox, with insights from OECD and ECHA on its role in REACH and as an alternative to animal testing for chemical assessment.

Covers REACH requirements for QSAR-based adaptations, ECHA’s evaluation approach, and typical deficiencies identified in submitted QSAR studies.

Provides an overview of IUCLID dossier preparation and submission, detailing entities, dataset structure, validation, and the use of ECHA’s Cloud Services.