Outlines key concepts in toxicological risk assessment, including critical effects, guidance values, toxicokinetics, and uncertainty factors used in public health decision-making.

Presents Canada’s OHARA initiative to operationalize a One Health approach to risk assessment, emphasizing multisectoral coordination, environmental integration, and protocol development.

ECHA’s approach to group substance assessments, upcoming improvements in communication to registrants, and how to respond if your substance is included.

An overview of risk assessment methodology, emphasizing the steps from hazard identification to exposure characterization and the use of scientific evidence in defining safety thresholds.

Presents industry perspectives on QSAR and read-across for regulatory toxicology, focusing on genotoxicity assessment of pesticide residues and the integration of chemical similarity, metabolism, and structural alerts.

Covers key features and future plans for the QSAR Toolbox, including integration with IUCLID and applications in non-animal hazard assessment.

Explores the concept, misconceptions, and future potential of AOPs in predictive toxicology, featuring case studies from nanosafety and discussing their integration with data-driven and high-throughput strategies.

Introduces the fundamentals of deep learning and its application in toxicology, with a focus on model construction, input data handling, and potential uses such as QSAR enhancement.

Webinar on stakeholder use of the OECD QSAR Toolbox, with insights from OECD and ECHA on its role in REACH and as an alternative to animal testing for chemical assessment.

Covers REACH requirements for QSAR-based adaptations, ECHA’s evaluation approach, and typical deficiencies identified in submitted QSAR studies.

Discusses the potential of non-animal models to transform safety assessment and therapeutic development, with insights from pandemic-driven advances in regulatory science.