This webstream addresses the role of the SSbD approach in industrial transformation, exploring opportunities, challenges, and its wider uptake at national and regional levels within the chemical sector.

This webinar presents an overview of frameworks and methodologies for integrating safety and sustainability in the innovation process for nanomaterials, highlighting tools, systems, and platforms compiled in the recent OECD SSbD report.

Recording of a Venice School 2025 session introducing a case-specific, quantitative MCDA approach for SSbD. It features methods for identifying multi-optimal solutions and integrating stakeholder perspectives in decision-making.

This workshop introduces Safe and Sustainable by Design (SSbD) scenarios for advanced and incremental innovations, focusing on tailored approaches for chemical and material risk assessment.

Covers SSbD policy context, scoping actions, and a case-based walkthrough of the PLANETS Workflow, with full supporting materials and worksheet.

Discover insights into nanomaterials' human and environmental toxicology, as well as of emissions and exposure in all stages of the lifecycle of a nanomaterial. This research supports Safe(r)-and-sustainable-by-design approaches in developing and producing novel materials.

This webinar explores the exposome framework in toxicology, focusing on multi-stressor interactions, long-term effects, and regulatory implications for environmental health.

Explore the SUNSHINE e-learning focusing on Safe-and-Sustainable-by-Design (SSbD) for advanced nanomaterials. Access recordings and presentations from workshops, webinars, and annual meetings, offering insights into digital tools and sustainability innovations.

Focused on occupational safety, this report explores training needs for workers handling nanomaterials and advanced materials. It includes insights from stakeholder consultations and outlines guidelines for harmonized risk management training across Europe.

Outlines key concepts in toxicological risk assessment, including critical effects, guidance values, toxicokinetics, and uncertainty factors used in public health decision-making.

Presents Canada’s OHARA initiative to operationalize a One Health approach to risk assessment, emphasizing multisectoral coordination, environmental integration, and protocol development.

Covers the role of industrial toxicology in regulatory compliance, product stewardship, and risk-based evaluation across sectors including chemicals, pharmaceuticals, and consumer goods.

An educational resource offering scientific insights and practical examples on human biomonitoring to support chemical risk assessment and public health decision-making.

This seminar discusses in vitro tools to assess toxicology of chemical mixtures.

Presents industry perspectives on QSAR and read-across for regulatory toxicology, focusing on genotoxicity assessment of pesticide residues and the integration of chemical similarity, metabolism, and structural alerts.

Introduces next-generation PBK modeling and its role in translating in vitro concentrations to human-relevant exposures for risk assessment, highlighting key parameters, tools, and case studies.

The session outlines how stakeholder comments have influenced revisions to the proposed framework. It also includes a presentation of the updated framework and key changes introduced.

Explore the EU Commission's proposed framework for Safe and Sustainable by Design (SSbD). This workshop discusses its stepwise process, assessment methods, and key aspects of implementation. Case studies and next steps in the criteria’s development are also explored.

Introduces the fundamentals of deep learning and its application in toxicology, with a focus on model construction, input data handling, and potential uses such as QSAR enhancement.

Webinar on stakeholder use of the OECD QSAR Toolbox, with insights from OECD and ECHA on its role in REACH and as an alternative to animal testing for chemical assessment.

Covers REACH requirements for QSAR-based adaptations, ECHA’s evaluation approach, and typical deficiencies identified in submitted QSAR studies.

Concludes a week-long series of expert discussions with a plenary overview of NanoHarmony’s efforts to support OECD test guideline development, stakeholder collaboration, and long-term regulatory impact for nanosafety.

Discusses the potential of non-animal models to transform safety assessment and therapeutic development, with insights from pandemic-driven advances in regulatory science.

This presentation focuses on exhaled breath condensate (EBC) as a biological matrix for chromium biomonitoring, explaining its production, potential applications, and the procedures for sample collection. It outlines the method developed by the Health & Safety Laboratory in the UK for chromium speciation in EBC, supported by findings from a feasibility study. 

This presentation focuses on the molecular pathways involved in the development of asbestos-related diseases, emphasising the roles of oxidative stress, DNA repair, and xenobiotic metabolism. It explores how both germline mutations and single-nucleotide polymorphisms (SNPs) within these pathways influence individual susceptibility. By understanding these mechanisms, researchers can identify clinically relevant biomarkers that support early diagnosis and risk assessment.

This presentation focuses on the basic principles of matrix and biomarker selection in human biomonitoring, guiding participants from the identification of exposure biomarkers to their application in population studies.