Discover insights into nanomaterials' human and environmental toxicology, as well as of emissions and exposure in all stages of the lifecycle of a nanomaterial. This research supports Safe(r)-and-sustainable-by-design approaches in developing and producing novel materials.

Explore the SUNSHINE e-learning focusing on Safe-and-Sustainable-by-Design (SSbD) for advanced nanomaterials. Access recordings and presentations from workshops, webinars, and annual meetings, offering insights into digital tools and sustainability innovations.

Focused on occupational safety, this report explores training needs for workers handling nanomaterials and advanced materials. It includes insights from stakeholder consultations and outlines guidelines for harmonized risk management training across Europe.

Slide-based resource on OECD test guidelines, supporting science-regulation knowledge transfer, harmonisation, and onboarding of new Test Guideline developers (comtains 4 different modules).

Focused on the Safe(r) and Sustainable Innovation Approach (SSIA), this resource explores the integration of safety and sustainability into material design, regulatory anticipation, and collaborative knowledge-sharing frameworks to keep pace with rapid material innovation.

This handbook provides a comprehensive guide to nanosafety, with sections on data management, nanoinformatics, and emerging topics. Included is a detailed subsection on Safe-and-Sustainable-by-Design (SSbD), addressing the framework for safety and sustainability in material innovation.

Concludes a week-long series of expert discussions with a plenary overview of NanoHarmony’s efforts to support OECD test guideline development, stakeholder collaboration, and long-term regulatory impact for nanosafety.

Exploring nanoscience in short episodes, this series presents nanoparticles’ fundamentals, addressing topics like risks, applications, and lifecycle stages. Developed with expert input, it offers clear, concise insights for understanding their societal and scientific relevance.

This presentation focuses on the basic principles of matrix and biomarker selection in human biomonitoring, guiding participants from the identification of exposure biomarkers to their application in population studies. 

This presentation focuses on the molecular pathways involved in the development of asbestos-related diseases, emphasising the roles of oxidative stress, DNA repair, and xenobiotic metabolism. It explores how both germline mutations and single-nucleotide polymorphisms (SNPs) within these pathways influence individual susceptibility. By understanding these mechanisms, researchers can identify clinically relevant biomarkers that support early diagnosis and risk assessment.

Focuses on the health risks associated with asbestos exposure, emphasizing its link to a range of diseases including asbestosis, pleural conditions, and multiple forms of cancer. Highlights malignant mesothelioma as a particularly aggressive cancer of the pleura and peritoneum, primarily caused by asbestos exposure. Discusses current challenges in diagnosing mesothelioma and the ongoing investigation into potential serum biomarkers, such as Soluble Mesothelin Related Protein (SMRP), Fibulin-3, and Survivin, for improving early detection and monitoring treatment response.

Focuses on exploring the role of gene-environment interactions in disease development, using asbestosis as a case study to illustrate the combined impact of genetic and environmental factors. Highlights findings from a nested case-control study that incorporated cumulative asbestos exposure, smoking data, and PCR-based genotyping, with logistic regression used to assess risk. Emphasises the importance of investigating how genetic factors interact with lifestyle and occupational exposures to shape disease outcomes.

Introduces the Safe Innovation Approach, combining Safe by Design and Regulatory Preparedness to address safety early in the innovation process, with a focus on nanomaterials.