PARC organised an in-person training course on Health Risk Assessment of Chemicals – Principles and Applications, which took place from 18 to 22 November 2024 at the Karolinska Institutet, Campus Solna, Stockholm, Sweden, under the scientific coordination of the Institute of Environmental Medicine. ↗ 

Training content
• Introduction to the concepts and aims of health risk assessment
• The role of risk assessment in the wider risk analysis framework
• Steps of risk assessment: hazard identification, hazard characterisation, exposure assessment, and risk characterisation
• Use of data from in vivo, in vitro, and epidemiological studies, as well as exposure data, with emphasis on assessing relevance and reliability
• Introduction to new approach methodologies (NAMs), adverse outcome pathways (AOPs), and integrated approaches to testing and assessment (IATA)
• Derivation of health-based guidance values, such as Acceptable Daily Intake (ADI), and margins of safety
• Case studies on the application of risk assessment in regulatory decision making

Target audience
The course was designed for PhD students, researchers, and participants from authorities seeking to strengthen their understanding of the principles and applications of health risk assessment of chemicals. Participants were expected to have a background in toxicology or related fields.

Practical details
The course was free of charge and open to both PARC members and non-members, with priority given to PARC members. Participants covered their own travel, accommodation, and personal expenses.

Training highlights
For a detailed summary of the training outcomes and participation, please click here. Training materials developed and used during the training were not made publicly available, but you can find other related training resources in the PARC Repository of Learning and Educational Materials.