PARC is organising the second edition of the remote training course on “Exercises on results of in silico models and read-across using VEGAHUB – Examples related to cosmetics and ecotoxicological and environmental properties”, continuing its series of hands-on trainings focused on the practical interpretation and application of in silico tools...

On 3-4 March 2025, PARC hosted the remote training course " Use and interpretation of the results of in silico models and read-across", aimed at strengthening expertise in predictive toxicology. This training was coordinated by Istituto Mario Negri (IRFMN), Italy, under the scientific leadership of Emilio Benfenati, and provided participants...

PARC is organising a second remote training course on in silico models and read-across, this time focusing on hands-on interpretation and practical application using the VEGAHUB platform. The training will take place on 23-24 October 2025, with morning or afternoon sessions depending on participant numbers. The course is coordinated by...

PARC is organising a remote training course on the use and interpretation of in silico models and read-across, with a special focus on VEGAHUB and applications related to human, ecotoxicological, and environmental properties. The online course will take place on 3-4 March 2025. The scientific coordination is provided by the...

On 23-24 October 2025, PARC held its second online training course on in silico models and read-across using VEGAHUB, coordinated by the Istituto Mario Negri (IRFMN), Italy. This follow-up course attracted 42 participants from 21 countries across Europe and beyond, eager to build their practical skills. Unlike the first VEGAHUB...

Iseult Lynch, professor and researcher at the University of Birmingham, has devoted her career to understanding the interactions between nanomaterials and biological systems. Initially focused on nanomaterials in medical devices, Lynch has expanded her research to explore their broader impact on human health, investigating how nanoparticles interact with proteins, cells...

What does the future of chemical safety look like? For 38 researchers, regulators, and scientists from around the world, the answer became clearer earlier this month in Brno, Czech Republic. Gathered for an intensive three-day training on new approach methodologies (NAMs) and hazard assessment, they explored cutting-edge tools that are...

In the context of preparing its roadmap to phase out animal testing for chemical safety assessment - a key priority for both ethical science and modern regulatory policy - the European Commission organised a series of three workshops to gain input from stakeholders. The second workshop, held in Brussels on...

As part of its mission to strengthen Europe’s capacity to assess, monitor and reduce chemical risks, the Partnership for the Assessment of Risks from Chemicals (PARC) has completed a dedicated campaign of interviews with its Chemical Leaders, the experts guiding scientific progress across PARC’s priority areas. This series brings visibility...

The use of artificial intelligence (AI) and machine learning (ML) has revolutionized the world in recent years. Within PARC, a survey has been launched on landscape and readiness of computational new approach methodologies based on ML and AI approaches for next generation risk assessment of chemicals. This survey examines whether...

Nikiforos Alygizakis, researcher at the National and Kapodistrian University of Athens, has dedicated his career to detecting and understanding contaminants of emerging concern. Using advanced mass spectrometry and non-target screening, he has led large-scale monitoring campaigns across Europe, helping to reveal the hidden complexity of chemical mixtures in our environment...

An important step toward stronger collaboration in chemical hazard assessment has been achieved through an initial mapping of Europe’s research capacities. By collecting insights from over 70 leading experts across 20 countries, the initiative lays the foundation for enhanced cooperation, harmonised methodologies, and shared infrastructures, paving the way for a...

To further support its mission, PARC has established SYNnet, a network designed to facilitate collaboration and knowledge sharing with other initiatives, projects, organisations. Since its inception, SYNnet has made substantial progress in fostering synergies and collaborations. An agreement was signed with the Joint Research Centre (JRC), and the process to...

How can we better protect our brains and hormone systems from chemical risks? PARC group of experts dedicated to Hazard Assessment recently shared preliminary results and key regulatory questions at ECHA Science Seminars, highlighting how chemical hazard assessment can better protect both the developing and adult brain, and help avoid...

Adverse Outcome Pathways (AOPs) are central to next-generation chemical hazard assessment. They map how a molecular interaction triggered by a chemical can lead, step by step, to an adverse outcome in a cascading manner. AOPs provide a shared framework through which scientists and regulators identify key biological events, clarify evidence...

The field of chemical risk assessment is evolving rapidly with the introduction of innovative approaches like Physiologically-Based Kinetic (PBK) models. These models, which simulate what the body does to a chemical rather than focusing on what the chemical does to the body, play a crucial role in modernising how we...

The PARC consortium has provided the vital building blocks for the development of a robust early warning system (EWS) for hazardous chemicals in a new report. The development of an EWS for hazardous chemicals is a pivotal element of PARC’s commitment to safeguarding public health and environmental quality. The EWS...