Increased wildfire activity increases the demands onfire rescue services and firefighters’ contact with harmful chemicals.This study aimed to determine firefighters’ exposure to toxicmetal(loid)s and its association with the lipid profile. CELSPAC-FIREexpo study participants (including 110 firefighters) providedurine and blood samples to quantify urinary levels of metal(loid)s (arsenic, cadmium (Cd), mercury...

The rapid increase in the production and global use of chemicals and their mixtures has raised concerns about their potential impact on human and environmental health. With advances in analytical techniques, in particular, high-resolution mass spectrometry (HRMS), thousands of compounds and transformation products with potential adverse effects can now be...

Global change confronts organisms with multiple stressors causing nonadditive effects. Persistent stress, however, leads to adaptation and related trade-offs. The question arises: How can the resulting effects of these contradictory processes be predicted? Here we show that Gammarus pulex from agricultural streams were more tolerant to clothianidin (mean EC 50...

The AOP-Wiki, a knowledge database for Adverse Outcome Pathways (AOPs), requires an efficient way to present an overview of its content for the reconstruction of networks by experts in a given domain. We have developed a user-friendly tool using artificial intelligence, the AOP-networkFinder , that retrieves AOPs of interest, modifies...