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News

PARCopedia: growing community, new tools, and a focus on participation

PARCopedia: growing community, new tools, and a focus on participation

PARCopedia is steadily expanding as a hub for knowledge sharing and collaboration in chemical risk assessment, now counting 1,260 registered users from across Africa, the Americas, Europe, Asia, and Oceania. With 62% of members affiliated with PARC and 38% joining independently, the platform has become a space that connects academia...

metrological traceability, interlaboratory comparisons, and rerence materials in chemical measurements

PARC training course on metrological traceability, interlaboratory comparisons, and rerence materials in chemical measurements

PARC is offering a specialised one-day online training course on metrological traceability, interlaboratory comparisons, and reference materials in chemical measurements. The course will take place on 17 October 2025, under the scientific coordination of the Genetal Chemical State Laboratory, Greece. What to expect: A comprehensive overview of metrological traceability and...

3rd SYNnet Forum

Third PARC SYNnet Forum held in Athens

The Third PARC SYNnet Forum took place on Wednesday, 17 September 2025, at the Megaron Athens International Conference Centre, back-to-back with the EUROTOX 2025 congress. The Forum brought together researchers, regulators, and stakeholders to exchange knowledge on advancing chemical safety assessment through new scientific approaches and collaborative networking. The two-hour...

Training - 2nd in silico models and read-across

PARC online training: exercises with in silico models and read-across using VEGAHUB

PARC is organising a second remote training course on in silico models and read-across, this time focusing on hands-on interpretation and practical application using the VEGAHUB platform. The training will take place on 23-24 October 2025, with morning or afternoon sessions depending on participant numbers. The course is coordinated by...

224 results

Events

Using Omics Bioactivity Data to Increase Confidence in Chemical Groups

The webinar on Using Omics Bioactivity Data to Increase Confidence in Chemical Groups, organised by PrecisionTox, took place online on 10 December 2025. The session examined how omics bioactivity data can enhance confidence in chemical grouping and presented perspectives from both regulatory authorities and industry, highlighting the role of grouping...

Pesticides & Organic Micropollutants Conference 2025

The European Conference on Pesticides and related Organic Micropollutants in the Environment 2025 (PESTIPOLL 2025) will convene experts from environmental chemistry, analytical science, regulatory policy and academia to address the detection, behaviour and risk assessment of pesticides and organic micropollutants. The event explores advanced instrumentation, data integration and monitoring across...

Fourth SYNnet Workshop on Synergies with External Initiatives

SYNnet is pleased to invite you to the 4 th Workshop on Synergies with External Initiatives, which will be held virtually on 19 November 2025, from 10:00 to 12:30 CET. Join us to explore opportunities for collaboration between PARC and key initiatives from the ExpoHealthNet Cluster. The link for online...

Endocrine Disruptors - 16th International Akademie Fresenius Conference

The 16 th International Akademie Fresenius Conference on Endocrine Disruptors brings together leading scientists, regulators, and industry professionals to explore the latest regulatory and scientific developments in the identification, assessment, and management of endocrine-disrupting chemicals. With evolving regulation and advances in new approach methodologies, the event serves as a key...

83 results

Projects

Innovative approaches to assess developmental and adult neurotoxicity 

Overview Developmental and adult neurotoxicity describe harmful effects on the developing or mature nervous system. They are currently assessed using specific studies and according to international guidelines, such as those from the Organisation for Economic Co-operation and Development ( OECD). These guideline studies require significant resources, making them impractical for...

Assessing chemicals exposure of waste management workers

Key messages The project will provide valuable EU-specific data on chemical exposures and risks faced by workers in e-waste and plastics waste streams. It will generate evidence to support policies aimed at worker protection, public health, chemical safety, and environmental sustainability. By fostering training and knowledge exchange, the project will...

From emission to impact: modelling chemical pathways to human exposure

Key messages Modelling of exposure from the source to the exposure is based on a mechanistic understanding of processes involved in the project from the source to the human exposure. Source to dose modelling requires in most cases an integrated approach, meaning the considering of different exposure routes (inhalation, oral...

Advancing detection mechanisms of hazardous chemicals in food

Key messages The project focuses on improving food safety by detecting hazardous chemicals, including unknown and emerging contaminants, in food products. Traditional testing methods only target known compounds, but this project uses high-resolution mass spectrometry to identify a broader range of potential food contaminants. The project explores how advanced screening...

166 results

Publications

Computational tools to facilitate early warning of new emerging risk chemicals

Computational tools to facilitate early warning of new emerging risk chemicals

Innovative tools suitable for chemical risk assessment are being developed in numerous domains, such as non-target chemical analysis, omics, and computational approaches. These methods will also be critical components in an efficient early warning system (EWS) for the identification of potentially hazardous chemicals. Much knowledge is missing for current use...

A comprehensive item bank of internal validity issues of relevance to in vitro toxicology studies

A comprehensive item bank of internal validity issues of relevance to invitro toxicology studies

Context : In vitro toxicology studies are increasingly being included as evidence in systematic reviews and chemical risk assessments. INVITES-IN, a tool for assessing the internal validity of in vitro studies, is currently under development. The first step in developing INVITES-IN involves the creation of an “item bank”, an overview...

High precision blood lead radiogenic isotope signatures in a community exposed to Pb contaminated soils and implications for the current Pb exposure of the European population

High precision blood lead radiogenic isotope signatures in a community exposed to Pb contaminated soils and implications for the current Pb exposure of the European population

Our study provides the most comprehensive dataset for high-precision radiogenic isotopes of lead (Pb) in blood for the western European population. It investigates their potential for elucidating the contribution of soil Pb to blood Pb using a human biomonitoring survey involving 81 adults and 4 children living in the urban...

A conceptual framework for landscape-based environmental risk assessment (ERA) of pesticides

A conceptual framework for landscape-based environmental risk assessment (ERA) of pesticides

While pesticide use is subject to strict regulatory oversight worldwide, it remains a main concern for environmental protection, including biodiversity conservation. This is partly due to the current regulatory approach that relies on separate assessments for each single pesticide, crop use, and non-target organism group at local scales. Such assessments...

78 results

Deliverables

Technical specifications of the study: Project design, hypotheses and research questions as well as analytical procedures including QA/QC and data flows

Data management plan

Catalogues on environmental and biomonitoring networks Y1

Ethics and data protection policy

99 results

Learning materials

Educational material on Safe by Design and nanotech

This webpage features Safe-by-Design educational materials developed by RIVM. Resources include an English-language course, serious games, and domain-specific tools for integrating safety into innovation processes. Materials are suitable for curricula or independent use by students and professionals.

Education and Safe by Design

Explore educational resources on this website to learn about safety in biotechnology and the Safe-by-Design (SbD) approach. Materials are adaptable for use in academic, research, and project contexts, aiding students and researchers in applying SbD principles.

Making innovation Safe by Design

This video animation presents an introduction to the complexities of making innovation safe by design. It examines the fundamental hurdles and offers a practical overview of risk assessment principles for those developing sustainable and responsible solutions.

Safe(r) and Sustainable Innovation Approach (SSIA): Nano-Enabled and other Emerging Materials

Focused on the Safe(r) and Sustainable Innovation Approach (SSIA), this resource explores the integration of safety and sustainability into material design, regulatory anticipation, and collaborative knowledge-sharing frameworks to keep pace with rapid material innovation.

203 results

Partners

Hellenic Food Authorithy

Leof. Kifisias, Athina 115 26

Rīga Stradiņš University

Dzirciema str. 16, LV-1007

Institute of Marine Research

Nordnesgaten 50, 5005

Polytechnic of Leiria

Campus 1 Rua Dr. João Soares Apt 4045, 2411-901

251 results

Laboratories

Slovak Medical University in Bratislava (SMU)

Limbová 12, 833 03 Bratislava

Institute of Environmental Assessment and Water Research, Spanish Research Council (IDAEA-CSIC)

C. Jordi Girona 18-26, 08034 Barcelona

Institute of Health Carlos III (ISCIII)

Ctra. de Pozuelo, 28, 28222 Majadahonda

Sederma / Croda

29 Rue du Chemin Vert, 78610 Le Perray-en-Yvelines

Le Perray-en-Yvelines