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News

PARC’s repository of learning and educational materials now available

PARC is now making scientific knowledge more accessible by offering a comprehensive collection of both PARC-developed and external learning and educational materials on risk assessment. Topics covered include exposure science, hazard and risk assessment, and safe and sustainable by design. Designed for a broad community of stakeholders, including researchers, students...

IB meeting - 2025

PARC International Board convenes to advance harmonisation, innovation, and global collaboration

The PARC International Board gathered for its second quarterly meeting at ANSES in Paris, with hybrid participation from PARC Management Board members and invited experts. The meeting focused on strengthening the long-term impact of the partnership through enhanced harmonisation of chemical inventories, the integration of emerging scientific endpoints into risk...

Join the workshop launching the alpha version of the PARC SSbD toolbox

The European Partnership for the Assessment of Risks from Chemicals (PARC) is pleased to announce a dedicated online workshop to mark the alpha release of the Safe and Sustainable by Design (SSbD) toolbox. The event will take place on 3 July 2025 and will introduce the toolbox’s key features, provide...

WP5 meeting in Oslo

Advancing hazard assessment: Highlights from the WP5 Annual Meeting in PARC

The PARC Work Package 5 (WP5) “Hazard assessment” Annual Meeting has successfully concluded after three energising days. Held from 12 to 14 May 2025 in Oslo and hosted by the Norwegian Institute of Public Health (NIPH), the event brought together over 100 in-person participants and 60 online attendees, representing 44...

224 results

Events

REACH Conference 2025 – Chemical Management & EU Chemicals Legislation & Product Safety

The REACH Conference 2025, organized by EKOTOX Centers, is an international gathering addressing the evolving landscape of chemicals regulation and product safety in the European Union. This year’s edition will focus on current and upcoming aspects of EU chemicals legislation — such as the REACH revision (REACH 2.0), CLP implementation...

German Language Branch of the Society of Environmental Toxicology and Chemistry Annual Meeting

The SETAC German Language Branch (GLB) organizes its annual meeting for scientists, policymakers, and practitioners from Germany, Austria, and Switzerland engaged in environmental toxicology and chemistry. The meeting provides a forum to present research, discuss regional and global challenges, and foster collaboration across institutions working on environmental health, ecology, and...

Introduction to Data Management Practices

The Introduction to Data Management Practices course, organised by the National Bioinformatics Infrastructure Sweden (NBIS), will be held from 17 to 19 March 2026, in Uppsala, Sweden, with an optional pre-course Q&A session held online on 10 March 2026. This three-day course is designed to help researchers in the life...

Data Visualisation with R

The SIB Data Visualisation with R course took place on 16-17 December 2025 in Zurich. It was designed to help scientists create clear, effective, and visually compelling representations of their data. This hands-on training guided participants through the principles of designing data visualisations for scientific communication. From selecting the most...

83 results

Projects

Enhancing the reusability of human biomonitoring data for improved health risk assessment

Key messages This project makes human biomonitoring datasets more accessible and reusable for science and regulation by preparing and sharing them as FAIR resources – findable, accessible, interoperable, and reusable – while respecting the sensitivity of personal data. We built practical enablers – harmonised metadata, schema mappings, and search –...

Innovative approaches to assess developmental and adult neurotoxicity 

Overview Developmental and adult neurotoxicity describe harmful effects on the developing or mature nervous system. They are currently assessed using specific studies and according to international guidelines, such as those from the Organisation for Economic Co-operation and Development ( OECD). These guideline studies require significant resources, making them impractical for...

Assessing chemicals exposure of waste management workers

Key messages The project will provide valuable EU-specific data on chemical exposures and risks faced by workers in e-waste and plastics waste streams. It will generate evidence to support policies aimed at worker protection, public health, chemical safety, and environmental sustainability. By fostering training and knowledge exchange, the project will...

Understanding risks from BPA alternatives on the environment

Key messages Investigation of the potential adverse effects (e.g. apical endpoints such as mortality, effects related to the anticipated mode of action or MIE, effects on reproduction, effects on endocrine system) of certain individual substances and “real-life” mixtures of BPA alternatives on non-mammalian organisms belonging to different taxa The project...

166 results

Publications

How wastewater reflects human metabolism - Suspect screening of pharmaceutical metabolites in wastewater influent

How wastewater reflects human metabolism - suspect screening of pharmaceutical metabolites in wastewater influent

Pharmaceuticals and their human metabolites are contaminants of emerging concern in the aquatic environment. Most monitoring studies focus on a limited set of parent compounds and even fewer metabolites. However, more than 50% of the most consumed pharmaceuticals are excreted in higher amounts as metabolites than as parents, as confirmed...

Exploring BPA alternatives – Environmental levels and toxicity review

Exploring BPA alternatives – Environmental levels and toxicity review

Bisphenol A alternatives are manufactured as potentially less harmful substitutes of bisphenol A (BPA) that offer similar functionality. These alternatives are already in the market, entering the environment and thus raising ecological concerns. However, it can be expected that levels of BPA alternatives will dominate in the future, they are...

Regulatory and practical considerations on the implementation of a mixture allocation factor in REACH

Regulatory and practical considerations on the implementation of a mixture allocation factor in REACH

There is indisputable evidence that the environment, humans and wildlife are continuously exposed not to single but to multiple chemicals from diferent sources. Exposure to these mixtures can lead to combined risks not yet suffciently addressed in any of the European chemical legislations. Under the REACH regulation for industrial chemicals...

Two-stage machine learning-based approach to predict points of departure for human noncancer and developmental/reproductive effects

Two-stage machine learning-based approach to predict points of departure for human noncancer and developmental/reproductive effects

Chemical points of departure (PODs) for critical health effects are crucial for evaluating and managing human health risks and impacts from exposure. However, PODs are unavailable for most chemicals in commerce due to a lack of in vivo toxicity data. We therefore developed a two-stage machine learning (ML) framework to...

78 results

Deliverables

Annual Summary Report (ASR) Y1

Annual Work Plan (AWP) Y1 including rolling Strategic Research and Innovation Agenda (SRIA)

99 results

Learning materials

Human Biomonitoring. Basics: educational course

An educational resource offering scientific insights and practical examples on human biomonitoring to support chemical risk assessment and public health decision-making.

Improving mixtures health assessments: Combining in silico with in vitro/in vivo models to evaluate co-occurring contaminants

The webinar focus on methods to evaluate combined exposures and chemical mixtures, using computer models and in vivo/in vitro testing.

Clearing some of the highest FAIR hurdles: PIDs, metadata, and semantic interoperability for researchers

Focuses on addressing FAIR data challenges in research, highlighting persistent identifiers, metadata, and semantic interoperability through expert presentations and interactive discussions.

Navigating chemical health risk assessment

Outlines key concepts in toxicological risk assessment, including critical effects, guidance values, toxicokinetics, and uncertainty factors used in public health decision-making.

203 results

Partners

Örebro University

Fakultetsgatan 1, 702 81

Danish Environmental Protection Agency

Tolderlundsvej 5, 5000 c

Swiss Federal Office for the Environment

Worblentalstrasse 68, 3063

French Authority for Nuclear Safety and Radiation Protection

31 Av. de la Division Leclerc, 92260

Fontenay-aux-Roses

251 results

Laboratories

National reference center for pesticide residues

Trnavská cesta 52, 826 45, Bratislava

Department of Clinical Sciences / Toxicology Laboratory

Facultad de Ciencias de la Salud, Paseo Blas Cabrera "Físico" s/n, 35016, Las Palmas de Gran Canaria

Las Palmas de Gran Canaria

Laboratory of the Waste Agency of Catalonia

Passatge del Criadero 1-3, Polígon Industrial Pla Sota el Molí, 08160 Montmeló (Barcelona)

Public Health Laboratory

C. Emigrantes, 20, Hortaleza, 28043 Madrid