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News

Science Digest recap 2024

In the fast-moving world of scientific research, staying up to date about recent findings on chemicals and their impact on health and the environment is vital. This is where the PARC Science Digest newsletter comes into play, providing news about relevant chemical research in a user-friendly way. In 2024, the...

2024: A year of progress for the SSbD toolbox

The Safe and Sustainable by Design (SSbD) initiative is a pre-market approach developed by the European Commission to ensure products meet stringent safety and sustainability goals throughout their lifecycle. Within PARC, it continued to gain momentum in 2024, driving innovation toward safer chemicals and materials. This year, PARC made significant...

Webinar on risk communication

PARC webinar series on risk communication launched

PARC has successfully launched its webinar series on risk communication, aiming to address the importance of effectively communicating health risks of chemicals to diverse stakeholders and building capacities within the PARC community and beyond. The first webinar, “ Principles for Effective Risk Communication", took place on 28 November 2024, attracting...

Progress in showcasing results from PARC research projects

The European Partnership for the Assessment of Risks from Chemicals ( PARC) has reached an exciting milestone in making research results more accessible to the public. Fourteen projects from across all four of the Partnership’s key topic areas have now been published on the PARC projects webpage. This development is...

224 results

Events

Introduction to Research Data Management (RDM) in Life Sciences

The Introduction to Research Data Management (RDM) in Life Sciences training course took place on 17 October 2025 in Ghent, Belgium. This training was designed to help researchers integrate RDM practices into their projects from the outset, with a strong focus on supporting the publication process. Throughout the day, participants...

Introduction to Research Data Management - Getting started with Data Management and Data Stewardship

The Introduction to Research Data Management - Getting started with Data Management and Data Stewardship training course will take place in the Belval Campus, University of Luxembourg, from 29 September to 2 October 2025. Through a mix of lectures and hands-on sessions, participants will explore all stages of the data...

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Adverse Outcome Pathways: From Principles to Practice

The SCAHT webinar series “ Adverse Outcome Pathways: From Principles to Practice” will take place online monthly, beginning on 29 July 2025. This five-part webinar series will introduce key concepts and applications of Adverse Outcome Pathways (AOPs). Each 45-minute session, held on Tuesdays from 12:00 to 12:45 CET, features leading...

10th Norwegian Environmental Toxicology Symposium – Environmental Research and the One Health Concept

The 10 th Norwegian Environmental Toxicology Symposium (NETS 2025) will take place at the University of Stavanger, focusing on environmental research and the One Health concept. The symposium aims to bring together the Norwegian scientific community, environmental managers, and industry stakeholders to address environmental challenges and share sustainable solutions for...

166 results

Publications

A comprehensive battery of flow cytometric immunoassays for the in vitro testing of chemical effects in human blood cells

A comprehensive battery of flow cytometric immunoassays for the in vitro testing of chemical effects in human blood cells

Background: There is a growing need for immunological assays to test toxic and modulatory effects of chemicals. The assays should be easy to use, reproducible and superior to cell line-based assays. We have therefore developed a comprehensive portfolio of assays based on primary human blood cells that are suitable for...

Applicability of food monitoring data for assessing relative exposure contributions of pyrethroids in retrospective human biomonitoring risk estimations

Applicability of food monitoring data for assessing relative exposure contributions of pyrethroids in retrospective human biomonitoring risk estimations

The use of pyrethroids is very broad and shows increasing trends. Human biomonitoring studies represent the best approach for realistic risk estimations, but their interpretation requires a tiered approach. A previous HBM4EU study indicated levels in European children groups just around the threshold for concern, requiring further refinement. The main...

Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health

Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health

Fungi of the genus Alternaria are ubiquitous plant pathogens and saprophytes which are able to grow under varying temperature and moisture conditions as well as on a large range of substrates. A spectrum of structurally diverse secondary metabolites with toxic potential has been identified, but occurrence and relative proportion of...

Acetylcholinesterase inhibition in rats and humans following acute fenitrothion exposure predicted by physiologically based kinetic modeling-facilitated quantitative in vitroto in vivo extrapolation

Acetylcholinesterase inhibition in rats and humans following acute fenitrothion exposure predicted by physiologically based kinetic modeling-facilitated quantitative in vitro to in vivo extrapolation

Worldwide use of organophosphate pesticides as agricultural chemicals aims to maintain a stable food supply, while their toxicity remains a major public health concern. A common mechanism of acute neurotoxicity following organophosphate pesticide exposure is the inhibition of acetylcholinesterase (AChE). To support Next Generation Risk Assessment for public health upon...

99 results

Learning materials

Risk communication essentials

WHO’s Emergency Risk Communication course, outlining key concepts, core modules, and strategies to support effective communication during public health emergencies.

QSAR and read-across in the assessment of plant protection products

Presents industry perspectives on QSAR and read-across for regulatory toxicology, focusing on genotoxicity assessment of pesticide residues and the integration of chemical similarity, metabolism, and structural alerts.

In vitro assays for (bio)monitoring of chemical mixtures - from the environment to people

This seminar discusses in vitro tools to assess toxicology of chemical mixtures.

203 results

Partners

Swedish Environmental Protection Agency

Virkesvägen 2, Hammarby Sjöstad

The Capital Region of Denmark

Kongens Vænge 2, 3400

Swiss Federal Institute of Aquatic Science and Technology

Ueberlandstrasse 133, 8600

EHESP French School of Public Health

15 Av. du Professeur Léon Bernard, 35043

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Laboratories

Department of environmental analyses (Chair of biopharmaceutics and pharmacokinetics)

Aškerčeva cesta 7, 1000 Ljubljana

Laboratory Department (DELAB)

Av. de les Drassanes, 13, 08001. Barcelona

Chemical Analysis laboratory

Avda. Punto Com, 2. 28805. Alcalá de Henares. Madrid

Alcalá de Henares

National reference center for pesticide residues

Trnavská cesta 52, 826 45, Bratislava