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News

PARC Aligned Study

Monitoring human exposure to chemicals: PARC Aligned Studies

As part of PARC, an EU-wide human biomonitoring (HBM) survey is being conducted by aligning national and regional human biomonitoring studies across Europe, building on the work previously done by the Human Biomonitoring Initiative in Europe, HBM4EU. This ambitious project includes participation from 24 countries and focuses on collecting data...

National Hub Sweden

Exploring Sweden´s collaborative approach to chemical risk assessment

In Sweden, a collaborative initiative, the so-called Governmental Authority Hub, is shaping the future of chemical risk assessment. The Hub, created even before the launch of PARC, has brought together a myriad of representatives from different Swedish national authorities. Their mission? To align Sweden's strategies with PARC and to foster...

PARC course on Chemical Exposure & Modelling

PARC course on Chemical Exposure & Modelling successfully held in Brno

The course on Chemical Exposure & Modelling, part of the PARC training plan for 2024-2025, was successfully held between 10-12 June in Brno, Czech Republic. With 25 trainees from 13 countries (Belgium, Croatia, Czech Republic, Germany, Greece, Chile, Latvia, Luxembourg, Poland, Portugal, Slovak Republic, Slovenia and Spain), the course offered...

PARC workshop T4.2 and T8.1

Significant progress achieved in chemicals prioritisation and Early Warning Systems at PARC workshop

Two key aspects in chemicals management are prioritising chemicals for enhanced monitoring and setting up an Early Warning System for detection of emerging issues. Last week (4-5 June 2024), PARC experts on these topics met at a workshop at University of Athens. Synergies and alignments between the Early Warning System...

224 results

Events

Scientific Reporting and Writing

The Scientific Reporting and Writing course was held on-site at UMIT Tirol from 23 to 25 October 2025, with an online preparation phase beginning on 22 September 2025. Designed as a blended learning experience, the course aimed to strengthen participants’ skills in scientific reporting, writing, and presentation. Through a combination...

Introduction to Infectious Disease Epidemiology – Principles, Dynamics and Control Measures

Short overview This course provides a comprehensive introduction to infectious disease epidemiology. It covers transmission dynamics, control strategies, outbreak investigation, surveillance, and public health response. Additional topics include vaccination study design, causal inference methods, and an introduction to infectious disease modelling and outbreak simulation. The course combines lectures, hands-on exercises...

Advanced Systematic Reviews and Meta-Analysis

Short overview This online course provides an introduction to advanced methods in systematic reviews and meta-analysis, including frequentist and Bayesian approaches, diagnostic accuracy, and network meta-analysis. It combines interactive lectures with hands-on tutorials and practical exercises. Target audience Researchers, health professionals, students, and consultants with basic statistical knowledge and experience...

Causal Inference for Assessing Effectiveness in Real World Data and Clinical Trials: A Practical Hands-on Workshop

This training course will take place on-site at UMIT Tirol, Austria, from 19–23 May 2025, and offers 5 ECTS credits. It introduces key concepts and methods in causal inference, with a strong focus on real-world applications in health technology assessment and policy. The five-day programme combines lectures, case discussions, group...

University for Health Sciences, Medical Informatics and Technology

Eduard-Wallnöfer-Zentrum 1, 6060 Hall in Tirol, Austria

166 results

Publications

New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens—a PARC project

New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens—a PARC project

Carcinogenic chemicals, or their metabolites, can be classified as genotoxic or non-genotoxic carcinogens (NGTxCs). Genotoxic compounds induce DNA damage, which can be detected by an established in vitro and in vivo battery of genotoxicity assays. For NGTxCs, DNA is not the primary target, and the possible modes of action (MoA)...

Firefighters and the liver: Exposure to PFAS and PAHs in relation to liver function and serum lipids (CELSPAC-FIREexpo study)

Firefighters and the liver: Exposure to PFAS and PAHs in relation to liver function and serum lipids (CELSPAC-FIREexpo study)

Introduction: Firefighting is one of the most hazardous occupations due to exposure to per- and polyfluoroalkyl substances (PFAS) and polycyclic aromatic hydrocarbons (PAHs). Such exposure is suspected to affect the cardiometabolic profile, e.g., liver function and serum lipids. However, only a few studies have investigated the impact of this specific...

Development of a rat physiologically based kinetic model (PBK) for three organophosphate flame retardants (TDCIPP, TCIPP, TCEP)

Development of a rat physiologically based kinetic model (PBK) for three organophosphate flame retardants (TDCIPP, TCIPP, TCEP)

Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), Tris (1-chloro-2-propyl) phosphate (TCIPP) and tris (2-chloroethyl) phosphate (TCEP) are three widely used organophosphate flame retardants (OPFRs) being frequently detected in human body fluids. Although OPFRs are being detected in human beings, the toxicological effects of their exposure are not clearly understood due to limited data. For...

Development of new approach methods for the identification and characterization of endocrine metabolic disruptors—a PARC project

Development of new approach methods for the identification and characterization of endocrine metabolic disruptors-a PARC project

In past times, the analysis of endocrine disrupting properties of chemicals has mainly been focused on (anti-)estrogenic or (anti-)androgenic properties, as well as on aspects of steroidogenesis and the modulation of thyroid signaling. More recently, disruption of energy metabolism and related signaling pathways by exogenous substances, so-called metabolism-disrupting chemicals (MDCs)...

203 results

Partners

Norwegian Institute for Air Research

Instituttveien 18, 2007

University of Aveiro

Universidade de , 3810-193

Medical University of Vienna

Spitalgasse 23, 1090 Wien

University of Las Palmas de Gran Canaria

C. Juan de Quesada, 30, 35001 , Las Palmas

Las Palmas de Gran Canaria

251 results

Laboratories

Laboratory for Occupational and Environmental Hygiene, Environment and Health, Department of Public Health and Primary Care

Herestraat 49, box 952, B-3000 Leuven

Department of Environmental Protection, Health and Environmental Risk Analysis Team

Al. Mickiewicza 30, 30-059 Krakow

Area of atmospheric pollution - National Center for Environmental Health

Carretera de Majadahonda-Pozuelo Km. 2.200, 28220, Majadahonda

Environmental Health Department - Air and Occupational Health Unit

Av. Padre Cruz, 1649-016 Lisboa